Mpox: A Global Health Concern and How to Stay Safe During the Holidays

As the year-end holiday season approaches, Malaysians and individuals worldwide are reminded of the critical need to be vigilant about health concerns, particularly the risk posed by mpox. This reminder comes from medical experts like Dr. Aaron Lai Kuo Huo, who emphasizes the importance of awareness, prevention, and knowing the necessary steps to take if exposed to mpox. The virus, which shares similarities with smallpox, remains a prevalent threat, especially in central and west Africa. Recent surges in cases highlight the importance of caution during this festive season when travel and social interactions increase significantly. Understanding the nature of mpox, its transmission, and preventive measures is essential for ensuring a safe and healthy holiday period.

Mpox, or monkeypox, is caused by a virus closely related to the smallpox virus, though it is generally less severe. There are two main types of mpox: clade 1, which is endemic in central Africa, and clade 2, endemic in west Africa. The current outbreak in Africa is primarily due to the clade 1 strain, known for its high transmission rates and severe symptoms. Alarmingly, a new variant, clade 1b, has emerged with enhanced human-to-human transmission capabilities and the ability to evade immune detection. This development necessitates close monitoring as it could affect vaccine effectiveness and lead to higher rates of complications. Such mutations underscore the dynamic nature of viral pathogens and the continuous need for research and vigilance.

The transmission of mpox occurs through close physical contact with an infected person, contaminated objects, or sexual contact. It can also spread from animals to humans through direct contact with infected animals in endemic areas. Preventing transmission involves avoiding close, skin-to-skin contact and sharing personal items with infected individuals. Good hand hygiene is also crucial in curbing the spread of the virus. Initial symptoms of mpox include flu-like symptoms followed by a rash that starts on the face and spreads to other parts of the body. The rash progresses through stages, from flat spots to raised bumps, blisters, and pus-filled lesions, potentially leading to complications like secondary bacterial infections.

In light of these risks, individuals who suspect they have been exposed to mpox should isolate themselves immediately to prevent further spread and seek medical advice for testing and diagnosis. It is especially important to avoid contact with vulnerable groups such as immunocompromised individuals and pregnant women. Testing for mpox typically involves swabs from skin lesions or the nasopharynx. Those at greater risk include individuals with weakened immune systems, pregnant women, and those with multiple sexual partners. Pregnant women face a higher risk as mpox can affect both the mother and fetus, potentially leading to miscarriage, stillbirth, or preterm delivery.

Efforts to raise awareness about mpox are being intensified globally, as evidenced by initiatives like those undertaken by the Laredo Public Health Department. Although no cases have been reported in Laredo, the proactive stance aligns with the CDC’s call for increased vigilance in the United States. Health officials stress the importance of vaccination, hygiene, and community cooperation to protect the community from potential outbreaks. Vaccinations are available to everyone, regardless of insurance status, and residents are encouraged to seek medical advice if they experience symptoms of mpox, which may include a rash, fever, and swollen lymph nodes.

Community engagement is a key aspect of the strategy to combat mpox, with efforts to inform schools, organizations, and businesses about available resources. Globally, over 100,000 cases of clade ii mpox have been reported since 2022, primarily in regions where the virus was previously undocumented. This has led to concerted efforts to educate and vaccinate populations to curb transmission. Clade ii mpox, while less severe than clade i, continues to spread through direct and intimate contact. The US Department of Health and Human Services advises against vaccination for those who have recovered from mpox or had a severe allergic reaction after the first dose, but encourages others, especially those who may have been exposed, to get vaccinated.

Mpox’s global impact has been significant enough for the World Health Organization to declare it a global health emergency. The virus, which can cause a rash and flu-like symptoms, spreads most commonly through sexual contact but can also be transmitted through close contact with an infected person. The ongoing outbreak of clade ii mpox in many countries, including the U.S., highlights the importance of recognizing symptoms and taking precautions. While over 99% of people who contract clade ii mpox recover, understanding how the virus spreads and the importance of avoiding close contact with infected individuals remains crucial.

Transmission of mpox is primarily through skin-to-skin contact, kissing, or sexual activity, but it can also occur via contaminated surfaces. In some regions, handling infected animals or consuming undercooked meat can lead to infection. Unlike COVID-19, mpox is not easily spread through the air and is not transmitted through properly chlorinated water. While anyone can contract mpox, high-risk groups include those with weak immune systems, children under one year old, and pregnant women. Extra precautions should be taken by people living with or caring for someone with mpox, as well as healthcare workers, to prevent transmission.

Symptoms of mpox include fever, chills, headache, muscle aches, and swollen lymph nodes, with a rash usually appearing a few days later. The virus has an incubation period of 3-17 days during which an infected person may not show any symptoms. To protect oneself from mpox, it is important to avoid close contact with infected individuals, refrain from sharing personal items, and practice regular handwashing. A vaccine is available and recommended for high-risk individuals and those traveling to outbreak areas. While vaccination is important, taking precautions to avoid close contact with infected individuals remains essential.

In Malaysia and Asia, the World Health Organization’s declaration of mpox as a global health concern has emphasized the importance of being informed and prepared. Despite being less severe and contagious than smallpox, mpox requires awareness and readiness to ensure a safe and healthy holiday season. The virus, still prevalent in Central and West Africa, has two main clades with different characteristics and transmission rates. Clade 1 is more common in Central Africa and known for severe symptoms, while Clade 1b, more prominent in West Africa, is more easily transmitted between humans and can evade immune detection.

To combat the spread of mpox, health officials have implemented key measures, including understanding the virus and taking preventive steps. Researchers at JNCASR have made significant progress in studying the monkeypox virus, highlighting its potential danger and the need for continued research. They isolated the virus from a patient in the Democratic Republic of Congo, conducted genomic sequencing, and identified several mutations associated with increased virulence. Their findings underscore the importance of remaining vigilant about potential viral threats like mpox, especially in the context of the ongoing global health emergency caused by the COVID-19 pandemic.

As we navigate the complexities of mpox and its implications for global health, it is crucial to remain informed and proactive. By understanding the virus, its transmission, and preventive measures, individuals can protect themselves and their communities. The collaborative efforts of health officials, researchers, and the public are essential in tackling the threat of mpox and ensuring a safe and healthy future. As the world continues to grapple with the challenges posed by emerging infectious diseases, the lessons learned from mpox will undoubtedly contribute to our collective ability to respond effectively to future health crises.